AstraZeneca Covid Drug 'Cocktail' Reduces Risk of Severe Disease Or Death

AstraZeneca had production and distribution issues with its Covid vaccine, but its antibody - like Merck's - appears to provide yet another weapon in the growing arsenal arrayed against the virus. JL

CNBC reports:

The drug, called AZD7442, reduced the risk of developing severe Covid-19 or death by 50% in patients who had been symptomatic for seven days or less, meeting the main goal of the trial. “An early intervention with our antibody can give a significant reduction in progression to severe disease, with continued protection for more than six months,” AstraZeneca is also developing the drug cocktail as a therapy to protect people who do not have a strong enough immune response to Covid-19 vaccines.

AstraZeneca’s experimental Covid-19 antibody drug cocktail succeeded in reducing severe disease or death in non-hospitalized patients in a late-stage study, the British drugmaker said on Monday.

The drug, called AZD7442, reduced the risk of developing severe Covid-19 or death by 50% in patients who had been symptomatic for seven days or less, meeting the main goal of the trial.

“An early intervention with our antibody can give a significant reduction in progression to severe disease, with continued protection for more than six months,” said Mene Pangalos, executive vice president, biopharmaceuticals R&D at AstraZeneca.

The company will discuss the data with health authorities, it added, without elaborating.

AstraZeneca is also developing the drug cocktail as a therapy to protect people who do not have a strong enough immune response to Covid-19 vaccines. It requested emergency approval from U.S. regulators for its use as a prevention drug last week.